9 results
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
#Diagnosis #IM ... #Honc #Anemia #Differential ... Iron #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
#Diagnosis #EM ... #IM #Honc #Anemia ... Workup #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Framework by MCV Microcytic ... Infections Macrocytic ... , B12 deficiency ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... • Alcohol • Drugs ... MatthewHoMD #Macrocytic
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... RBC: Pyridoxine deficiency ... (sometimes) Macrocytic ... Chemotherapy (e.g ... disorders, Oxidative drugs
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Blood Smear • Drugs ... Oval Macrocytes ... • Dietary Deficiency ... Increased Requirement (e.g ... Liver Disease #Macrocytic
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... Hypochromic & microcytic ... autoimmune disease, drugs
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... RBC>13 • Iron Deficiency ... Malabsorption, Dietary Deficiency ... TlBC > 18% • Anemia ... #Microcytic #Anemia
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... : • Worsening macrocytic ... anemia, yellow ... , can consider IM ... B12 #Cobalamin #Deficiency