8 results
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
Differential Diagnosis ... #IM #Honc #Anemia ... Iron #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Algorithm for the Evaluation of Anemia #Diagnosis #EM #IM #Honc #Anemia #Differential #Workup #Algorithm #Microcytic #Macrocytic
Evaluation of Anemia #Diagnosis ... #EM #IM #Honc # ... Workup #Algorithm #Microcytic ... #Macrocytic #Normocytic ... #Ddxof
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... (up to 100) = normocytic ... 95 (or 100) is macrocytic ... Workup #Hematology #Microcytic ... #Macrocytic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Framework by MCV Microcytic ... Sideroblastic anemia Normocytic ... Infections Macrocytic ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma Diagnosis ... replacement) - Usually normocytic ... but can be macrocytic ... pathologic fx) Diagnosis ... also >100 CMC IM
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... anemia (sometimes) Macrocytic ... Chemotherapy (e.g ... disorders, Oxidative drugs ... #differential #diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Blood Smear • Drugs ... Oval Macrocytes ... Increased Requirement (e.g ... Liver Disease #Macrocytic
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
dietary intake (e.g ... : • Worsening macrocytic ... , can consider IM ... consider other diagnosis ... Cobalamin #Deficiency #diagnosis