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myopathy treatment alcohol apml autoimmune behcet differential differentiation disease erythematosus etoh fungal hematology infections infectiousdiseases lupus muscle mycoses oncology sams
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... myopathies such as ... muscle fibers Risk ... Pitavastatin Risk ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... : >3 symptoms, or ... fluid overload, PCC ... #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
CNS symptoms (headache ... Reactive Arthritis, AS ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager Scoring Alcohol Withdrawal Syndrome (AWS): • PAWSS • CIWA-Ar •
Timeline: • Minor ... Withdrawal Symptoms ... 3% - High risk ... #AWS #diagnosis ... #treatment #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... RP-ILD), dermato-rheumatologic ... Other Diseases: • PBC ... #Myopathy #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
neuropathy, transverse myelitis ... effusion, INC risk ... Malignancy Risk ... #Rheumatology # ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Thrombosis highest risk ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... transplantation • MCC ... #Management #Infections
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