15 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia ... #pathophysiology ... #symptoms
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... and Management Algorithm ... factors: Previous acute ... factors affecting symptom ... common: Food, Acute
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... clinical context and signs ... ANCA, ANA, Anti-GBM ... • Cardio-renal syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... - ACS, AKI, acute ... WBC >100k, + lab signs ... : • Pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... arteritis • Acute ... #neurology #PHANTOMS
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute ... mental status or memory ... can improve symptoms ... development of Korsakoff syndrome ... Diagnosis #Management #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
(GBS) Acute autoimmune ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
PCB variants of GBS ... test - Cogan sign ... - Peek sign ... aspiration and acute ... diagnosis #management #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... ) • Acute: ... #treatment #MS