15 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... episodic and semantic memory ... AlzheimersDisease #Dementia ... #diagnosis #signs ... #symptoms
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... , signs, and complications ... : • As with ET ... • Treatment algorithms ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... : - Neuro: AMS ... changes, stroke symptoms ... WBC >100k, + lab signs ... diagnosis #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... not as common ... Responsive to Treatment ... pathophysiology #Hematology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
occur in utero as ... is also known as ... Signs/Symptoms/Complications ... Labia major & minor ... endocrinology #peds #pediatrics
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... It presents as an ... • Bicytopenia Treatment ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... development of skin symptoms ... , breast CA - Hematologic ... Treatment: - Systemic
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... with or without treatment ... , but without treatment ... syphilis may appear as ... Clinical #Photo #Dermatology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... life • M=F Symptoms ... and Signs: 50% ... and signs: • ... certain drugs (such as