12 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia ... #diagnosis #signs ... #symptoms
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... mucus membrane changes ... coronavirus #diagnosis #Signs ... #Symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... intolerance, Poor memory ... slowness, Psychosis/dementia ... Carpal timel syndrome
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... - Behavioral changes ... - Behavioral changes ... Workup #Diagnosis #Geriatrics
Pediatric SVT - Management Algorithm
Identify SVT:
 • HR not variable
 • Abrupt rate changes
 • Infants:
Pediatric SVT - ... Management Algorithm ... • Abrupt rate changes ... Signs of shock or ... #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... tinnitus, visual changes ... , stroke symptoms ... WBC >100k, + lab signs ... organ damage • Treatment
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Criteria (2 of 4): • Changes ... mental status or memory ... Anorexia nervosa Treatment ... can improve symptoms ... development of Korsakoff syndrome
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Romana's sign ... Indeterminate form (No signs ... /symptoms, positive ... q12h)x60 days • Pediatric ... 90-120 days • Pediatric
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... • Depressive symptoms ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... life • M=F Symptoms ... and Signs: 50% ... mental status changes ... and signs: •