54 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary Biliary ... pathophysiology #pbc ... #psc #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Autoimmune hepatitis, PBC ... Extrahepatic - Biliary ... - Obstruction: Biliary ... differential #diagnosis #algorithm
Indications for ERCP
1. Biliary Tract Diseases:
 • Biliary obstruction: Choledocholithiasis, Malignant biliary strictures, Benign biliary strictures
Indications for ERCP ... Biliary Tract Diseases ... Oddi manometry • Bile ... Therapeutic ERCP ... major papilla #ERCP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Ducts - PBC ... - CBD stone, Biliary ... Transaminitis #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Highest • Bone • Liver ... Cholangitis (PBC ... - Other biliary ... diseases/Bile duct
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... cholestasis → Cirrhosis/Liver ... No extrahepatic biliary ... or higher • Liver ... malignancy #Primary #Biliary
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
hepatitis, Acute biliary ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Extrahepatic • Biliary ... Causes #Acute #algorithm
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Liver biopsy findings ... #Biliary #Cirrhosis ... #Diagnosis #Algorithm
Liver Flukes on ERCP
Here are liver flukes (Fasciola hepatica) extracted from the bile duct during ERCP
Liver Flukes on ... ERCP Here are liver ... duct during ERCP ... intestines and liver ... #Flukes #ERCP #
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Ducts • PSC ... Duct Stone • Biliary ... Differential #Diagnosis #Algorithm