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differential causes pediatrics amenorrhea anemia anomaly bleeding chronic congenital dermatology developmentaldelay elevatedmcv fatigue gynecology history ischemia macrocytic macrocytosis mesenteric naildisorders
Causes of Congenital Anomalies - Differential Diagnosis Algorithm Malformation • Embryonic development failure or inadequacy (often multifactorial) Deformation
- Differential Diagnosis ... normal tissue (e.g ... (Syndromic) • ... • Association (e.g ... #Peds #Pediatrics
Causes of Developmental Delay - Differential Diagnosis Algorithm Isolated Domain Delay - Reduced Respiratory Drive: • Cognitive
- Differential Diagnosis ... Algorithm Isolated ... (e.g. ... • Mechanical (e.g ... #Peds #Pediatrics
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm No onset of menarche by age 16 with secondary
Gonadal Dysgenesis (e.g ... Gonadal Dysgenesis (e.g ... Outflow Tract Anomalies ... • Functional (e.g ... . eating disorder
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Thrombus, 1° clotting disorder ... inflammation (e.g ... Antiphospholipid syndrome ... hypovolemia), Meds ... #algorithm
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Algorithm Endocrine ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... • Somatization Disorder ... Chronic Fatigue Syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal ... Increased Requirement (e.g ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... #History #peds ... #pediatrics #diagnosis
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