19 results
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Loop Diuretics (e.g ... 4) Thiazides (e.g ... HCTZ) 5) Potassium-sparing ... ) #Pathophysiology ... #Nephrology #Nephron
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Loop diuretic (e.g ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... nephron #diuretics #pharmacology ... #nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the Treatment ... Evidence-Based Off-Label Pharmacologic ... Treatments of Uremic ... nalfurafine 2.5 mcg ... #management #nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... cyclosilicate #Potassium ... #Hyperkalemia #treatment ... #pharmacology # ... table #comparison #nephrology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
by: - drugs (e.g ... neurodegenerative disorders (eg ... Pathophysiology: ... Treatment: anticholinergics ... PhysicalExam #clinical #neurology
Migraine Treatment Overview

 • What is a Migraine?
 • Pathophysiology
 • Common Migraine Triggers
 • Diagnosis
Migraine Treatment ... • Pathophysiology ... Prophylactic Treatment ... #management #pharmacology ... #prophylaxis #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology ... diagnosis #management #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology