40 results
Emergency management of severe hyperkalemia

#hyperkalemia #management #algorithm #nephrology #Potassium #Treatment
management of severe hyperkalemia ... #hyperkalemia ... management #algorithm #nephrology ... #Potassium #Treatment
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... Comparison #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... Fluids Shift potassium ... LouLectures #Hyperkalemia ... #nephrology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Loop Diuretics (e.g ... 4) Thiazides (e.g ... HCTZ) 5) Potassium-sparing ... ) #Pathophysiology ... #Nephrology #Nephron
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium ... #treatment #pharmacology ... table #comparison #nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Loop diuretic (e.g ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... nephron #diuretics #pharmacology ... #nephrology #medications
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... of hyperkalemia ... diagnosis #management #pathophysiology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... and ECG changes ... #potassium #high ... management #algorithm #treatment