12 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... coagulation defects. 1) HELLP ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
coagulation defects. 1) HELLP ... #TTPHUS #HELLP ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... #Disease #Pregnancy ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Differential Diagnosis ... Preeclampsia, HELLP ... #Pregnancy #hepatology ... #obstetrics #obgyn
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #Differential #Diagnosis ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... Septic shock, Obstetric ... Summary #table #comparison ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... • NASH, Chronic ... #differential #diagnosis
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
during pregnancy ... pits <100k), ↑ liver ... preeclampsia patients • HELLP ... hemolysis, elevated liver ... hypertension #htn #obstetrics
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Viral zoonotic disease ... Characteristic Rash ... • Fomites • Live ... Umbilification - Rash ... #MPOX #Diagnosis