9 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
made in the liver ... sinusoid (hepatic ... or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Hepatic congestionl ... Liver disease ... - Acute fatty liver ... #diagnosis #differential ... #hepatology #SAAG
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Complications • Ascites ... Esophageal Varices • Hepatic ... Spontaneous Bacterial Peritonitis ... Complications #diagnosis ... management #summary #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Diagnosis Chronic ... liver disease ( ... 5% Tuberculous peritonitis ... Disease, Fulminant Hepatic ... #hepatology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
(SBP) - Diagnosis ... and Management Ascites ... Presentation in septic ... response Give IV albumin ... dysfunction or liver
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... - Differential Diagnosis ... - Massive liver ... failure - Hepatic ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... portal HTN: • Ascites ... INR, bilirubin, albumin ... #causes #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
or venipuncture sites ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis