15 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG ... Interpretation #Differential ... #Analysis
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic ... liver disease ( ... Disease, Fulminant Hepatic ... Diagnosis #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Acute fatty liver ... #Causes #diagnosis ... #differential # ... hepatology #SAAG
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Diagnosis Algorithm ... Hypertension - Hepatic ... disease • Acute liver ... #Hepatology #causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... of portal HTN: ascites ... #Diagnosis #causes ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
or venipuncture sites ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... - Massive liver ... - Fulminant hepatic ... failure - Hepatic ... #Diagnosis #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... Cholesterol emboli • Septic ... #Diagnosis #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
• Albumin • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #