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differential hepatology management causes lfts transaminitis algorithm dermatology pathophysiology pt abnormal acute aptt blood gastroenterology pediatrics product prolonged reactions abscess
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... more specific for hepatic ... Transaminitis #diagnosis ... #differential #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... ) • Advanced Liver ... table #comparison #diagnosis ... #hematology #deficiency
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... injury) • Ischemic ... ) • Non-hepatic ... #Differential #Diagnosis ... #hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Vasculature • Hepatic ... #Injury #Differential ... #Diagnosis #Causes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Kidney Failure Coagulation ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... disease: > 2 • NASH
Shotgun Laboratory Testing for Severe Acute Livery Injury https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known #TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
for Severe Acute Livery ... Injury https ... ammonia-levels-and-hepatic-encephalopathy-patients-known ... #LiverInjury #Diagnosis ... #Workup #Hepatology
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 Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... disease, Hepatic ... presentation: Hepatic ... #Injury #Diagnosis ... #Algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
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