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rheumatology disease adultonset treatment aosd hepatology activation algorithm bilirubin congenital criteria dermatology hemochromatosis hemophagocytic hlh hyperbilirubinemia inherited lymphohistiocytosis macrophage major
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... maculopapular rash ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... /splenomegaly, liver ... #onset #Stills ... #rheumatology # ... management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
regarding the diagnosis ... and hematologic ... hemochromatosis; HIC, hepatic ... #management #hepatology ... #gastroenterology
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... - Typical skin rash ... Abnormalities in liver ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
Characteristic Rash ... • Fomites • Live ... both children and adults ... #MPOX #Diagnosis ... #Management #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... Petechial or purpuric rash ... thrombocytopenia • Liver ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+++ (Plt, Hb), Hepatic ... diseases: SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
asymptomatic young adults ... of hemolysis or liver ... Older children and adults ... • Defect in hepatic ... #diagnosis #gastroenterology
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