19 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... • Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Algorithm - Systemic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #Diagnosis #Algorithm
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
- Differential Diagnosis ... Diffuse Congenital - Generalized ... of hair, eyes, skin ... McCune Albright syndrome ... #Diagnosis #Algorithm
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... most frequent skin ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... SAPHO syndrome ( ... Secondary syphilis ... Sweet syndrome ... #Dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #Diagnosis #Algorithm
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... • Loose anagen syndrome ... to Skin Disease ... #Algorithm #causes
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Cryofibrinogenemia Diagnosis ... : • + Clinical ... Antiphospholipid syndrome ... hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... : • Clinical triad ... reticularis & skin ... Type III Often Secondary ... Labs/Diagnosis: