14 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... (eg, skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Thrombocytopenia #Lupus ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing ... #workup
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... constitutional symptoms ... comparison #table #rheumatology ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
symptoms by days ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Symptoms limited ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis