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diagnosis dermatology treatment hematology lupus sle blood canimorsus dermatomyositis druginduced erythematosus hemophagocytic hlh lymphohistiocytosis photo product reactions skin summary systemic
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Fulminans Skin Rash ... new full-body rash ... can lead to the rash ... BIDMC Infectious Diseases ... Fulminans #Skin #Rash
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Skin Rash 40 ... Diffuse blanching rash ... +purpuric rash → ... University Infectious Diseases ... Canimorsus #Skin #Rash
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... Conjunctivitis, Mucositis, Rash ... , Cough • +/-Nausea ... Polymorphous rash ... KD #vasculitis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... arthritis, Skin rash ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #Summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Fever is the main clinical ... Petechial or purpuric rash ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... #dermatology #rash ... #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... Evolution: Chronic disease ... comparison #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash ... Chronic B-cell activation
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