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diagnosis management rheumatology signs sle treatment druginduced erythematosus hematology oncology pathophysiology syndrome systemic acute aplastic avascularnecrosis blood bloodsmear canimorsus capnocytophaga
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Langerhan cells ... Subacute cutaneous lupus ... hair follicles -> causes ... diagnosis #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... Discontinuation of causal ... 40, F:M 9:1 • Clinical
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Clinical Presentation ... and petechiae Causes ... • Improve the symptoms
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
the red blood cells ... experience some symptoms ... related to anemia ... well as varying clinical ... These causes could
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Photosensitive rash ... lymphoproliferative syndrome Clinical ... lymphopenia, low PLT • Anemia ... : • Symptoms limited
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
The cells have assumed ... Note small size, darker ...

Causes of spherocyte ... and hemolytic anemias ... #Clinical #Path

Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
tissue: Epithelioid cells ... renal failure Clinical ... Features: • Many symptoms ... patients have no symptoms ... skin (16-32%): lupus
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... dog or cat bite. symptoms ... abrupt onset of symptoms ... #dermatology #clinical
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