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diagnosis rheumatology druginduced erythematosus management signs systemic acute comparison complications dil hiv manifestations mucocutaneous pathophysiology retroviral syndrome table treatment
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Langerhan cells ... hair follicles -> causes ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... Discontinuation of causal ... 40, F:M 9:1 • Clinical
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... lymphopenia, low PLT • Anemia ... : • Symptoms limited
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
(28%) • Skin rash ... decrease (<200 cells ... 14%), in which case ... enzymes ↑ • Mild anemia ... • New onset SLE
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... constitutional symptoms
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