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diagnosis management treatment druginduced nephrology rheumatology comparison complications differential dil hyperkalemia k mucocutaneous pathophysiology potassium rhabdomyolysis signs
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... 40, F:M 9:1 • Clinical ... #table #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... hair follicles -> causes ... #Manifestations ... diagnosis #signs #symptoms
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... Discontinuation of causal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Immobilization - Crush ... Dermatomyositis Clinical ... : • Triad of symptoms ... kidney tubular cells
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
tourniquet / IVF line draw ... only if no clear cause ... and Elimination (see ... Table below) ... Drives K+ into cells
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