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diagnosis dermatology myositis autoimmune clinical differential antimda5 antimda5dm antinxp2 antinxp2dm comparison gottrons gottronspapules heliotrope heliotroperash management myopathies papules shawl shawlsign
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of ... 1) heliotrope rash ... usually indicates myopathy ... Papules #Clinical #Photo
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... Dermatomyositis ... can present with rash ... and anti-HMGCR myopathy ... Myositis #diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... load Drug-induced myopathy ... 5-15% of lupus myopathy ... diagnosis #comparison #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... (blue-purple) rash ... • Erythematous rash ... Men • ~50% of cases ... #rheumatology #
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... with heliotrope rash ... out this is a case ... usually indicates myopathy ... dermatology #clinical #photo
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Symptoms: • Gottron rash ... syndrome • If myopathy ... statins - probably caused ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... (blue-purple) rash ... • Erythematous rash ... Muscle atrophy may cause ... diagnosis #management #rheumatology
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