43 results
Reversed Halo Sign - Infectious and Non-Infectious Differential Diagnosis
Definition: A focal rounded area of GGO surrounded
Reversed Halo Sign ... Non-Infectious Differential ... • Infectious Causes ... Non-Infectious Causes ... , Sarcoidosis, Dermatomyositis
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Lymphadenopathy - Differential ... Lymphoma, Head / Neck ... • Auto-immune: Dermatomyositis ... Lymphadenopathy #Differential ... Diagnosis #Algorithm #Causes
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... symptoms helps differentiate ... #Rash #Dermatomyositis ... Clinical #Photo #Neck
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of ... dermatomyositis ... 1) heliotrope rash ... , 2) shawl sign,
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... - Pathophysiology ... Ill-appearing, vital sign ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
SOB, N/V, stiff neck ... onset of fever, neck ... & hemorrhagic rash ... Vesicular & pruritic rash ... peds #pediatrics #pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... -> Heliotrope Rash ... flexors affected #Dermatomyositis ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... following passive neck ... Passive neck flexion ... causes spinal cord ... While the pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... shaking chills • Rash ... is rare (< 10% cases ... ), cough (30% cases