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diagnosis dermatology differential neurology rheumatology symptoms treatment clinical photo rhabdomyolysis summary syndrome als amyotrophic anaplasma anesthesia anesthesiology antimda5 antimda5dm antinxp2
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of ... dermatomyositis ... 1) heliotrope rash ... , 2) shawl sign,
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... -> Heliotrope Rash ... flexors affected #Dermatomyositis ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... shaking chills • Rash ... is rare (< 10% cases ... ), cough (30% cases
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Immobilization, Crush ... (polymyositis/Dermatomyositis ... ) AKI - Pathophysiology ... #Summary #causes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Diagnosis and Management ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Manifestations #pathophysiology ... #diagnosis #signs
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... erosions in ~20% Management
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
in Anaesthesia Causes ... Signs: hypotension ... • Petechial rash ... mainstay of initial management ... mainstay of initial management
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... with heliotrope rash ... , shawl sign, and ... out this is a case ... , 2) shawl sign,
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