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diagnosis management classification differential antiarrhythmics blood cardiology hcq hematology hydroxychloroquine kidney lupus pathophysiology product reactions vasculitis adverseeffects algorithm benefits calculi
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Metabolic • Renal ... Sclerosis • Stroke ... Myasthenia Gravis Pharmacologic ... Diagnosis #Algorithm #causes
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology #
Imaging Modalities for Renal Calculus AXR. KUB - Good far calcium-containing stones useful when limited radiation dose
Modalities for Renal ... X-rays useful tor stone ... identify non-calculus causes ... Combines calcific stone ... for non-calculus causes
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
1C: Strong Blockade ... receptors, and Ca ... MOA: Block slow Ca ... Vaughan #Williams #Pharmacology ... Classification #Classes
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Classification: CLASS ... 1C: Strong Blockade ... Antiarrhythmics #Pharmacology ... Classification #Classes
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Digestive intolerance nausea ... rare with ~100 cases ... of renal or hepatic ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... Palpable purpura: strong ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Palpable purpura: Strong ... carotodynia • TIA, stroke ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... Causes purpura & ... TRALI): Leading cause ... Host Disease (TA-GVHD ... diagnosis #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
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