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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Class I agents ... Blockers⠀ Class ... Blockers Class ... Blockers ⠀ Class ... #pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... duration: - CLASS ... duration - CLASS ... 1C: Strong Blockade ... Vaughan #Williams #Pharmacology
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... Widens QRS complex Class ... prolongs PR interval Class ... Prolongs QT interval Class ... Classification #Classes
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... - Strong Medicine ... #Blockers #ClassI ... Na #cardiology #pharmacology ... #table #comparison
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Classification: CLASS ... duration - CLASS ... duration - CLASS ... 1C: Strong Blockade ... & AP duration CLASS
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
Class III Antiarrhythmics ... - Potassium Channel ... Eric Strong @DrEricStrong ... - Strong Medicine ... #Blockers #pharmacology
SGLT2 inhibitors, also called gliflozins, are a class of medications that alter essential physiology of the
gliflozins, are a class ... sodium/glucose channels ... pharmaceutical class ... medications of this class ... member of this class
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Renal Epithelial Channels ... Nonspecific Cation Channel ... Heart Association class ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
exacerbations Drug Class ... Dosing: 250 mcg tablet ... have been a few changes ... #Indications #Pharmacology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
b) CHF c) CVA ... ASA class If ... Change in clinical ... • <6mo since stroke ... if result will change