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microscopy nephrology urine diagnosis clinical muddybrown acute ain atlas brown differential interpretation interstitial key nephritis sediment urinary
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Casts three ways ... #Brown #Granular ... #Casts #clinical ... urine #microscopy #MBGC
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Finely granular ... coarser granular ... coarse (c) and muddy ... brown (mb) granular
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
and granular/waxy ... mixed casts: ... /muddy brown granular ... , C and D: muddy ... #Casts #Urine #
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy - Casts ... Acellular Casts ... • Hyaline Casts ... • "Muddy Brown ... ) • Granular Casts
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... concentrated urine Granular ... breakdown of cellular casts ... "Muddy-brown" heme-granular ... casts are seen
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• White cell casts ... renal disease • Granular ... casts - More significant ... renal disease • “Muddy ... brown cast” - Necrotic
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... tubular proteinuria, granular ... casts/RTE; blend ... Nephritis #AIN #Algorithm
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