14 results
Examples of varying granular and granular/waxy mixed casts: 
A: coarse granular/broad-waxy (and surrounding white blood cells);
and granular/waxy ... surrounding white blood ... /muddy brown granular ... , C and D: muddy ... brown granular/
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast.

Dr. Vipin Varghese @vipvargh

#Muddy #Brown #Granular
Muddy Brown Granular ... Varghese @vipvargh #Muddy ... #Brown #Granular
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Finely granular ... slightly coarser granular ... coarse (c) and muddy ... brown (mb) granular
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... overt cytoplasmic granules ... , and Auer rods. ... KyleBradleyMD #Auer
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
a linear red "Auer ... of crystallized granules ... Path #BloodSmear #Blood ... Smear #Microscopy #Auer
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... with occasional Auer ... her peripheral blood ... decreased secondary granules ... Path #BloodSmear #Blood
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
concentrated urine Granular ... cellular casts "Muddy-brown ... " heme-granular ... disease Red blood ... Glomerulonephritis White blood
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
• "Muddy Brown ... ) • Granular Casts
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
renal disease • Granular ... renal disease • “Muddy
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... , Sudan Black, Auer ... @AmyChung #Blood