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clinical nephrology electronmicroscopy diagnosis microscopy glomerulus casts radiology amyloid deposits em urine desposition differential gbm glomerular pocus acute glomerulonephritis hematology
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
Examples of varying granular ... and granular/waxy ... /muddy brown granular ... , C and D: muddy ... brown granular/
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Varghese @vipvargh #Muddy ... #Brown #Granular
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Finely granular ... slightly coarser granular ... coarse (c) and muddy ... brown (mb) granular
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
concentrated urine Granular ... cellular casts "Muddy-brown ... " heme-granular
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... I see all of these ... leukemia #APL #APML #Pathology
Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization.
cytoplasmic trichohyalin granules ... EM shows intranuclear ... Trichodysplasia #spinulosa #Pathology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
• "Muddy Brown ... ) • Granular Casts
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image). Dutcher bodies are round,
bodies are round, agranular ... appear somewhat granular ... #Intranuclear #Pathology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
renal disease • Granular ... renal disease • “Muddy
Dysmorphic Red Blood Cells on Electron Microscopy This eyeSCANdy image shows dysmorphic red blood cells from the
ElectronMicroscopy #SEM ... #clinical #pathology
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