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diagnosis causes differential management immunology primarycare bloodstream c5c9deficiency catheter crbsi fever gonorrhea hematology humoral immunecompromised immunity immunocompromised infection lung pulmonary
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... pathogens Bacterial ... activation -> Complement ... #pathophysiology
Gonorrhea: Pathophysiology - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... eradication of pathogen ... Pathogen cleared ... activation of complement ... #Gonorrhea #Pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... (bacteria, viruses ... Opsonization: Abs coat pathogens ... Neutralization: Abs bind to pathogen ... Humoral #Immunity #pathophysiology
Causes of Sore Throat / Rhinorrhea - Differential Diagnosis Algorithm Common viral pathogens: Rhinovirus, Coronavirus, Influenza virus,
Differential Diagnosis Algorithm ... Common viral pathogens ... pathogen: Group ... Peritonsillar Abscess ... Differential #Diagnosis #Algorithm
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Pathophysiology ... Pathogens: • ... Aerobic Bacteria ... • Anaerobic Bacteria
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
infection - Management Algorithm ... Persistent fever and/or bacteremia ... endocarditis, epidural abscess ... • Resistant pathogens ... infection #Management #Algorithm
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Differential Diagnosis Algorithm ... HypospIenism • Bacteremia ... • Encapsulated Bacteria ... Infection • Abscess ... Periodontal Disease Complement
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• Pathophysiology ... NETs), cytokines, complement ... • Pathogens: ... Gram-positive/-negative bacteria ... source (e.g., abscess
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