17 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Rapidly Progressive ... RPGN has three primary ... RPGN #Rapidly #Progressive ... differential #diagnosis #algorithm ... #rheumatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... characterized by progressive ... strictures and eventual progression ... • CIRRHOSIS - Progression ... AutoImmuneLiver #PSC #Primary
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Digital ulcers, Primary ... crisis, Rapid progressive ... Autoantibodies #diagnosis #rheumatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... bile ducts - Progressive ... Cholestasis #PBC #Primary ... Pathophysiology #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... system (node) with progression ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #differential #algorithm
Morphology of Skin Lesions - Primary and Secondary - Description Algorithm
 • Primary Skin Lesion -
- Description Algorithm ... • Primary Skin ... infection), or natural regression ... #Description #Algorithm ... #dermatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
risk per year for progression ... risk per year for progression ... cells < 10% • Urinary ... h • Risk for progression ... amyloidosis • Rate of progression
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis Algorithm ... Pneumonia - slowly progressive ... inflammation Primary ... Differential #Diagnosis #Algorithm
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
vasculopathy and progressive ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
proteinuria, Rapidly progressing ... with GCA or as primary ... Rash, arthritis Primary ... is 50 years • Progressive ... immune GN (rapidly progressive