11 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... Action: Inhibits DPP ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... linagliptin) 5 mg DPP4 ... inhibitors work ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
They work primarily ... upset (since it works ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... Diabetes #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... #Medications #pharmacology ... comparison #table #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
Otherwise, it works ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
These work by inhibiting ... SGLT2 #Inhibitors #Pharmacology ... DM2 #Diabetes #Endocrinology
FIASP - Insulin Aspart vs Novolog

Have you heard about Fiasp, a new version of insulin aspart
Though it still works ... FastActing #Insulin #Pharmacology ... #EBM #Endocrinology
Adrenal Insufficiency Treatment - Stress Dose Steroids
 • Large Bore IVs, ~2L IVF & Draw workup
~2L IVF & Draw workup ... surgery with local anesthesia ... Stressor (general anesthesia ... StressDose #Steroids #endocrinology