201 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Diagnosis #Algorithm #Causes
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... crises”. ... Crises - Severe ... bulbar weakness
Drugs associated with worsening of Myasthenia Gravis (MG):
•	D-penicillamine 
•	Botulinum toxin.
•	Telithromycin
•	Fluoroquinolones 
•	Quinine
•	Magnesium
•	Macrolide antibiotics 
•	Corticosteroids (may cause transient
with worsening of Myasthenia ... Corticosteroids (may cause ... prevent prolonged myasthenic ... higher risk of myasthenic ... because of bulbar weakness
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... mild to moderate weakness ... or generalized weakness
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Eaton Syndrome, Myasthenia ... Neuromuscular #Weakness ... #Causes #differential
Diagnosis of Myasthenia Gravis - Physical Exam Maneuvers
 • Sustained lateral gaze for seconds to elicit
Diagnosis of Myasthenia ... ptotic eyelid will cause ... due to laryngeal weakness ... for neck flexor weakness ... BrighamMedRes #Myasthenia
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... neurologic disease • Myasthenia ... #differential #causes
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... NMJ disorder (Myasthenia ... #Generalized #Weakness ... Differential #Diagnosis #causes
Drugs Causing Acute Pancreatitis

Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... Class IV: Weakest ... #Pancreatitis #Causes
Causes of Facial Weakness - Differential Diagnosis Algorithm
Forehead Sparing = Central cause
  - Most commonly
Causes of Facial ... Weakness - Differential ... Sparing = Central cause ... AnnKumfer #Facial #Weakness ... Diagnosis #Algorithm #Causes