281 results
Myasthenia Gravis - Ptosis, Diplopia, Blurred Vision

Acute Myasthenic Crisis 
• Triggered by infection, medication 
• Respiratory
Myasthenia Gravis ... Vision Acute Myasthenic ... ventilation #Myasthenia ... #Gravis #Diagnosis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... - Differential Diagnosis ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... #Differential #Diagnosis
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... Diagnosis - ... Severe bulbar weakness ... #Gravis #diagnosis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
50 years in men Diagnosis ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... #Gravis #diagnosis
Drugs associated with worsening of Myasthenia Gravis (MG):
•	D-penicillamine 
•	Botulinum toxin.
•	Telithromycin
•	Fluoroquinolones 
•	Quinine
•	Magnesium
•	Macrolide antibiotics 
•	Corticosteroids (may cause transient
with worsening of Myasthenia ... prevent prolonged myasthenic ... higher risk of myasthenic ... because of bulbar weakness
Diagnosis of Myasthenia Gravis - Physical Exam Maneuvers
 • Sustained lateral gaze for seconds to elicit
Diagnosis of Myasthenia ... due to laryngeal weakness ... for neck flexor weakness ... BrighamMedRes #Myasthenia ... PhysicalExam #Maneuvers #Diagnosis
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... - Differential Diagnosis ... NMJ disorder (Myasthenia ... #Generalized #Weakness ... #Differential #Diagnosis
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Eaton Syndrome, Myasthenia ... Neuromuscular #Weakness ... #differential #diagnosis
Curtain Sign - Enhanced Ptosis in Myasthenia Gravis
Because of bilateral eyelid innervation, when the more affected
Enhanced Ptosis in Myasthenia ... Enhanced #Ptosis #Myasthenia ... Gravis #clinical #video
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... non-localized EOM weakness ... Myasthenia gravis ... eyelid #Ocular #Myasthenia ... PhysicalExam #clinical #video