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diagnosis hematology algorithm rheumatology causes anemia joint erythematosus lupus monoarthritis monoarticular msk oncology pain palpable petechiae polyarthritis polyarticular purpura skin
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
lymphoproliferative disorders ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders ... - Differential Diagnosis ... within 1 month of infection ... like “butterfly rash ... #msk #Differential
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Pediatrics Patient - Differential ... Diagnosis Malar rash ... Suggestive of Lyme infection ... gabrieltalledop #dermatology ... #differential #
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... parvovirus B19 infection ... Malar rash ... Sarcoidosis #dermatology ... #skin #rashes #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... , autoimmune disorder ... younger pts) Differential ... Monoclonal IgM Includes Disorders ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... inclusions - If infection ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm Infectious ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... SLE) - Viral infections ... APLS • Acute Infectious ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute infection ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Diagnosis #Causes #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... - Trauma - Infection ... Vasculitis - Collagen disorders ... #Differential # ... Algorithm #Causes #dermatology
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