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diagnosis management rheumatology sle activetb latenttb syndrome tuberculosis activation cerebritis comparison differential druginduced inflammatory iris macrophage mas neurology reconstitution summary
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus ( ... SLE) Clinical ... #Lupus #Erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... #Systemic #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... context of primary immune ... lupus erythematosus ... #Lupus #Erythematosus
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Fever is the main clinical ... (CNS) dysfunction ... lupus erythematosus ... Treatment: • Corticosteroids
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... months to years) Systemic ... Lupus Erythematosus ... • Immunologic Workup
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
system may react ... initiation Clinical ... pleural effusions, CNS ... fevers • MAC/NTM ... organizing PNA • Mycobacterium
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