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diagnosis rheumatology causes management dermatology algorithm neurology oncology erythematosus pulmonary sle syndromes systemic alopecia cardiology hairloss infections infectiousdiseases acute aki
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS ... #neurology #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... nervous system (CNS ... diagnosis and treatment ... • Systemic lupus ... #inflammatory #differential
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Status (AMS) - Differential ... • Cushing’s syndrome ... Hyperthyroidism CNS ... /agitation • CNS ... Vasculitis • Lupus
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS ... +GI+CVS+joints) ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Borrelia species, Mycobacterium ... Immunological Syndromes ... Churg-Strauss syndrome ... Sarcoidosis, Systemic lupus ... #Myocarditis #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... #Systemic #Lupus
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
antiphospholipid syndrome ... S - Systemic Lupus ... Mnemonic #diagnosis #differential ... #hematology
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