9 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
immunofluorescence Immune ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... #differential #diagnosis ... #algorithm #rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... #Diagnosis #Management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... disease, Kawasaki, Nephrotic ... Chronic infections, TB ... #Algorithm #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... nephritis, NPSLE ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... granulomatous nephritis ... fevers • MAC/NTM ... organizing PNA • Mycobacterium ... #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... nephritis, NPSLE ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... corticosteroids TREATMENT ... or other auto-immune ... #Diagnosis #Management ... #treatment #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... mediated disease • Immune ... , Hep A/B/CMV, TB ... Transverse Myelitis Treatment ... #management #neurology