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diagnosis management hemophagocytic lymphohistiocytosis comparison druginduced hemeonc macrophage mas reactions sle summary syndrome taco trali transfusion
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lymphohistiocytosis (HLH ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... excessive macrophage activation ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... constitutional symptoms • Treatment ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
sequestration and activation ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... recognition and treatment ... search for and treatment ... Treatment Approach ... Diagnosis #Management #Hematology
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