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diagnosis management druginduced erythematosus systemic activation ana antinuclear autoantibodies chemotherapy comparison cyp3a4 differential dil drugs hemeonc heparin hit induced inhibitors
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... specific inducers ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... constitutional symptoms • Treatment ... life-threatening • Treatment ... #table #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... 60-70%) & drug-induced ... , neonatal lupus ... erythematosus #diagnosis #rheumatology ... #table #ANA
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Drug Induced Systemic ... Lupus Erythematosus ... for 1 year of treatment ... medications #drugs #pharmacology ... differential #diagnosis #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... Confirmatory test ↑Se ... , Bivalirudin, DOAC ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment
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