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diagnosis management oncology activetb infections latenttb syndrome tuberculosis bronchiectasis cd4 differentiation emergencies evaluation hemeonc hivaids immune infectiousdiseases inflammatory iris mds
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... disease • Check CXR
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
common • Imaging: CXR ... - pulmonary opacities ... initiation • Differential ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... disease • Check CXR
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
M.tuberculosis, NTM ... Evaluation: Imaging (CXR ... Fungal, AFB), TB ... Infections #HIVAIDS #workup ... diagnosis #evaluation #differential
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
belonging to the Mycobacterium ... massiliense in CF ... Kansasii: • Mimics TB ... Hematologic malignancy ... #Infections #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
fevers • MAC/NTM ... organizing PNA • Mycobacterium ... leukoencephalopathy (PML ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Infection: TB ... , NTM, PNA • Primary ... Physical stigmata of cor ... mycobacteria Treatment ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... (~20 %) and APL ... renal failure, pulmonary
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