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diagnosis oncology basophils algorithm bandemia basophilia cbc hodgkins leucocytosis leukemoidreaction lymphoma lymphomas lymphoproliferative management mds myelodysplasia myelodysplastic neutrophil neutrophils nonhodgkin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... the total white blood ... Myeloproliferative Disorders ... (CML) - associated ... #hematology #basophils
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... (neutrophils, eosinophils ... disorders: > 100,000 ... part automated differential ... the underlying cause
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Treated Like Acute Leukemias ... #Classification ... #pathophysiology ... #Hematology #Diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... involve one, two, or all ... (CML) • Felty ... count with differential ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... ) Classification ... Immunohistochemical studies (to differentiate ... #hematology #oncology
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