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diagnosis hematology workup algorithm causes oncology chronic classification clinical acanthocytes agglutinin approach arthritis atlas bandemia bloodcell bloodsmear cbc cll cold
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Disease • Marrow ... Thalassemia • RBC ... • RBC Metabolism
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , McLeod blood group ... Unstable hemoglobin disorders ... #Morphology #differential ... diagnosis #hematology #microscopy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Algorithm Normal Blood ... Smear • Drugs ... Neutrophils - Low RBC ... • Small Bowel Disorder
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
X-linked disorder ... expression of Kell RBC ... granulomatous disease ... McLeod #Syndrome #Smear ... #Pathology #Microscopy
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... decreased PLT count: CBC ... plateletcount), peripheral blood ... changes), high MCV anemia ... ), HBsAg/anti-HBc
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Even with normal WBC ... relative to both WBC ... bacteremia • Abnormal WBC ... 21% had normal WBC
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Smear 23M Somali ... Hgb 12.5, WBC 14 ... Infectious Diseases ... recurrentis #BloodSmear #microscopy ... #pathology #clinical
Chronic Diarrhea - Differential Diagnosis Algorithm Steatorrhea - Maldigestive • Pancreatic Insufficiency - Primary
Chronic Diarrhea - Differential ... (Small Volume/ Bloody ... Cancer • Microscopic ... Colitis Disordered ... (Screen with CBC
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