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hematology management leukemia chronic cll lymphocytic aafp apl aplastic auerrods bacilliformis bartonella blood bloodsmear celiac cell classification differential disease fever
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... She was diagnosed ... hospitalization and treatment ... #Clinical #Path ... #Microscopy #Auer
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 Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... ordering a peripheral smear ... elevated, but anemia ... megaloblastic anemia ... #Macrocytic #Anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Algorithm Celiac ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... T1DM, Addisons, microscopic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Smear concerning ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... and petechiae Causes ... Treatment: ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Hematologic disease caused ... Lutzomyia verrucarum Clinical ... severe hemolytic anemia ... phase: Peripheral smear ... TREATMENT: ​• Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology
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