23 results
diagnosis management oncology differential rheumatology leukemia sle algorithm causes chronic classification erythematosus hemolysis lymphocytic microscopy systemic acidosis activation agglutinin analysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... differential #diagnosis #hematology ... #anemia
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... anemia (e.g. ... anemia Sickled ... disease Bite cells ... #anemia
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
anemia. ... DIC is a clinical ... and laboratory ... anemia is characterized ... #anemia #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... anemia, Thalassemias ... Hypophostphatemia Laboratory ... Peripheral Blood Smear ... Differential #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... #hemolytic #anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... extramedullary disease ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... result in severe anemia ... anemia Indirect ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... cells can indicate disease ... • Neutropenia, anemia ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... dyserythropoietic anemia
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