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lupus druginduced erythematosus signs systemic agglutinin antibody classification cold comparison cvid dil disease gca giantcell hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... reticulocytes • Hemolysis ... #Hemolytic #Anemia ... #diagnosis #management ... #treatment #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... • Compensated hemolysis ... #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... #autoantibodies ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... , Arthritis, myalgia ... months) and of autoantibodies ... comparison #table #rheumatology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... Kidney disease common ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... , Arthritis, myalgia ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... (NSHL) - (most common ... classification #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... very remarkable w/differential ... systemic complaints- anemia ... them, but urgent rheumatology ... #Diagnosis #Management
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