19 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... smear, HIV/HCV testing ... pylori test (GI symptoms ... ITP, unexplained pancytopenia ... #Causes #Workup
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Algorithm Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... for specific symptoms ... 1,500 cells/µL Workup ... #Differential #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Diagnosis: • hemolytic ... Positive Coombs testing ... Monoclonal IgM Includes Disorders
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider RBC membrane disorder ... #workup #hematology ... #testing
Pulmonary Hypertension Groups - WHO Classification
Group I - Vascular remodeling of pulmonary arteries
 • Idiopathic, HIV,
connective tissue disorders ... Sarcoidosis, chronic hemolytic ... disorders, sickle ... Symptoms of right ... #diagnosis
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Schistosomiasis - Chronic hemolytic ... anemia - Persistent ... #Diagnosis #Differential ... #Causes
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Framework Symptom ... URGENT WORKUP ... Esophageal Dysphagia: Testing ... the underlying cause ... gastroenterology #workup
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... musculoskeletal symptoms ... Psychiatric symptoms ... contribute to nonimmune hemolysis ... , or any other cause