9 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... >> MPA > eGPA • ... MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... diagnosis #algorithm
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... ) - ANCA Vasculitis ... Management Algorithm ... #ANCA #Vasculitis ... #Management #Treatment
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
polyangiitis (GPA ... polyangiitis (eGPA ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... Vasculitis: + MPO-ANCA ... (Dx: GPA, EGPA, ... differential #diagnosis ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
ANCA Associated ... polyangiitis - EGPA ... - GPA Cutaneous ... #rheumatology # ... differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... ): GPA (granulomatous ... subglottic stenosis) in GPA ... #diagnosis #management ... #treatment
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Kaposi's sarcoma • Rheumatologic ... / Autoimmune: ANCA-Assoc ... vasculitis (GPA ... > EGPA, MPA), Cryoglobulinemia ... #Diagnosis #pulmonary
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Cryoglobulinemia (MIXED) • ANCA ... - GPA - EGPA ... #Diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... myeloperoxidase (MPO-ANCA ... > PR3 60/ GPA ... Diagnosis #Rheumatology