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diagnosis oncology algorithm lymphocytic bandemia causes disorders hemeonc management markers mds myelodysplasia myelodysplastic neutrophil pathophysiology scleroderma syndromes thrombocytosis wbc workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Myelogenous Leukemia ... effect following treatment ... following EtOH induced thrombocytopenia ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... infiltrates (anemia, thrombocytopenia ... #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... ↑ WBC ... #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... Lymphocytosis: Absolute blood ... Neutropenia, anemia, thrombocytopenia ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Vmphocytosis on routine CBC ... uw_IMresidency #CLL ... #hematology #hemeonc
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... cultures, including blood ... #CBC #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... Leukemia • Idiopathic ... count with differential ... Syndromes #diagnosis #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
the mainstay of treatment ... frequent in men Chronic ... be seen after blood ... #Diagnosis #comparison ... #table #dermatology
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