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diagnosis oncology algorithm lymphocytic bandemia causes classification essential et hemeonc hodgkins lymphoma markers mds myelodysplasia myelodysplastic neutrophil pathophysiology scleroderma syndromes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Myelogenous Leukemia ... • Rheumatic disorders ... effect following treatment ... Algorithm #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... - CD7, CD3 Chronic ... ↑ WBC ... #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... infiltrates (anemia, thrombocytopenia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... in adults • Disorder ... Vmphocytosis on routine CBC ... #hematology #hemeonc ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... cultures, including blood ... #CBC #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Marrow Failure • Chronic ... Myelogenous Leukemia ... count with differential ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... Diagnosis: On the CBC ... PV, MDS, CML) Treatment ... Thrombocythemia #ET #hematology ... #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
the mainstay of treatment ... frequent in men Chronic ... be seen after blood ... #Diagnosis #comparison ... #table #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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